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Case Reports
Titration of Bivalirudin Infusion in the Pediatric Cardiac Catheterization Laboratory: A Case Report.
- Agathe Streiff, James DiNardo, and Katherine Zaleski.
- From the Department of Anesthesiology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York.
- A A Pract. 2019 Jul 15; 13 (2): 65-68.
AbstractBivalirudin is a direct thrombin inhibitor that is used as a procedural anticoagulant during percutaneous coronary interventions and cardiac surgery for patients with heparin-resistant thrombosis or heparin-induced thrombocytopenia. There is a robust literature describing its safety and efficacy in adults; however, its use in the pediatric population is relatively rare, with dosing extrapolated from adult data. In this case report, we describe a 4-year-old with complex congenital heart disease and history of heparin-induced thrombocytopenia who required bivalirudin dose uptitration during cardiac catheterization.
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