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Case Reports
Low-Dose Intrathecal Ziconotide for Spasticity From Primary Lateral Sclerosis: A Case Report.
- Xiaoying Zhu, Lynn R Kohan, and Robert B Goldstein.
- From the Department of Anesthesiology, Pain Management Center, University of Virginia Health System, Charlottesville, Virginia.
- A A Pract. 2019 Jul 1; 13 (1): 31-33.
AbstractSpasticity can be very debilitating and painful. We present a case of severe spasticity from primary lateral sclerosis refractory to intrathecal baclofen in doses up to 1100 μg/d. Baclofen was weaned down and switched to intrathecal ziconotide at 0.6 μg/d. The dose was then titrated up to 3 μg/d with excellent control of spasticity. This case suggests that low-dose intrathecal ziconotide should be considered in patients with lower extremity spasticity refractory to intrathecal baclofen.
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