• Biochimie · Jan 1978

    3-Chloroacetylpyridine adenine dinucleotide phosphate, an alkylating analogue of NADP+.

    • J F Biellmann, P Eid, P R Goulas, and C Hirth.
    • Biochimie. 1978 Jan 1; 60 (4): 417-9.

    AbstractAn alkylating analogue of NADP+ the 3-chloroacetylpyridine adenine dinucleotide phosphate was prepared from 3-diazoacetylpyridine adenine dinucleotide phosphate which was obtained by enzymatic transglucosidation of NADP+. The 3-diazoacetylpyridine adenine dinucleotide phosphate proved to be more unstable when compared to the corresponding NAD+ analogue. The alkylation of several dehydrogenases using this alkylating analogue is mentioned.

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