• Neurosurgery · Sep 2019

    Fundamentals of Clinical Prediction Modeling for the Neurosurgeon.

    • Hendrik-Jan Mijderwijk, Ewout W Steyerberg, Hans-Jakob Steiger, Igor Fischer, and Marcel A Kamp.
    • Department of Neurosurgery, Heinrich-Heine University Medical Center, Düsseldorf, Germany.
    • Neurosurgery. 2019 Sep 1; 85 (3): 302-311.

    AbstractClinical prediction models in neurosurgery are increasingly reported. These models aim to provide an evidence-based approach to the estimation of the probability of a neurosurgical outcome by combining 2 or more prognostic variables. Model development and model reporting are often suboptimal. A basic understanding of the methodology of clinical prediction modeling is needed when interpreting these models. We address basic statistical background, 7 modeling steps, and requirements of these models such that they may fulfill their potential for major impact for our daily clinical practice and for future scientific work.Copyright © 2019 by the Congress of Neurological Surgeons.

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