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- Chiarion Sileni Vanna V Istituto Oncologico Veneto, Padova., Mario Mandalà, and Paola Queirolo.
- Istituto Oncologico Veneto, Padova.
- Recenti Prog Med. 2017 Dec 1; 108 (12): 528-531.
AbstractCheckpoint inhibitors immunotherapy was a breakthrough in anti-tumor treatments. Anti-PD-1 monoclonal antibodies are now a standard of treatment for advanced melanoma patients, with a 3-year overall survival of over 50% and a low rate (<20%) of severe toxicities in the phase 3 studies. The aim of this review was to report the most important updates on anti-PD-1 drug pembrolizumab from ASCO (American Society of Clinical Oncology) and ESMO (European Society for Medical Oncology) 2017 Annual Meetings.
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