• Anaesth Intensive Care · Mar 2020

    Australian snake antivenom dosing: What is scientific and safe?

    • James Tibballs.
    • The Royal Children's Hospital, Melbourne, Australia.
    • Anaesth Intensive Care. 2020 Mar 1; 48 (2): 129-133.

    AbstractBecause the median dose of one vial 'clears the blood of circulating venom', the authors of the Australian Snakebite Project recommend restriction of antivenom to one vial for all envenomated victims. This is neither scientific nor safe. Methodological flaws in the case series include limited detection of venom toxins and misinterpretation of data. The recommendation fails to consider larger doses of venom than that neutralised by one vial of antivenom. Although one vial may be adequate for minor envenomation, the initial dose should be two vials with more on a clinical basis.

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