• Neurosurgery · Jan 2020

    Study Design in Neurosurgical Research: Considerations for Observational and Experimental Cohort Studies.

    • Christopher E Louie, Erin D'Agostino, Alexander Woods, and Timothy Ryken.
    • Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire.
    • Neurosurgery. 2020 Jan 1; 86 (1): 14-18.

    AbstractThere is inadequate neurosurgical literature discussing appropriate clinical study design. Here, we explore considerations for 2 fundamental study designs of epidemiology: experimental and observational cohort studies, through examples of theoretical yet realistic neurosurgical research questions. By examining 2 common neurosurgical procedures-namely, subdural drains for evacuation of chronic subdural hematoma, and the utility of navigation for placing external ventricular drains-we characterize the framework of cohort study models for clinical research applications.Copyright © 2019 by the Congress of Neurological Surgeons.

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