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J. Thorac. Cardiovasc. Surg. · Apr 2020
Editorial CommentBacterial infiltration and bioprosthetic valve failure: Emerging diagnostics for emerging therapies.
- Alexander P Kossar, Isaac George, Rachel Gordon, and Giovanni Ferrari.
- Division of Cardiothoracic Surgery, Department of Surgery, NewYork-Presbyterian Hospital/Columbia University Irving Medical Center, New York, NY.
- J. Thorac. Cardiovasc. Surg. 2020 Apr 1; 159 (4): 127912821279-1282.
AbstractDespite the increasing use of bioprosthetic heart valves (BHV), the mechanisms underlying BHV failure remain elusive. It has been suggested that bacteria in explanted native valves from patients without clinical or laboratory evidence of infective endocarditis may contribute to structural valve degeneration (SVD). In this editorial we discuss the potential roles of infection and thrombosis in BHV SVD.
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