• Curr Pain Headache Rep · Feb 2001

    Review

    Gender differences and hormonal modulation in visceral pain.

    • M M Heitkemper and M Jarrett.
    • Department of Biobehavioral Nursing and Health Systems, Box 357266, University of Washington, 1959 NE Pacific Street, T 618, Seattle, WA 98195, USA. heit@u.washington.edu
    • Curr Pain Headache Rep. 2001 Feb 1; 5 (1): 35-43.

    AbstractWomen seek healthcare and are diagnosed more frequently with chronic somatic and visceral pain conditions relative to men. These conditions tend not to be life-threatening disorders, but rather ones that decrease people's quality of life, impinge on work and recreational activities, and increase healthcare resource utilization. With increased awareness of basic gender differences in biology and responsiveness to therapies, there has been renewed interest in factors which may account for the gender disparity in chronic visceral pain conditions. Basic and clinical evidence primarily from patients with irritable bowel syndrome has provided initial insights into visceral pain sensitivity, perception, and responsitivity.

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