• Int J Obstet Anesth · Jan 1995

    Bradycardia and asystole following atropine-neostigmine administration after caesarean section in a parturient receiving methyldopa for pregnancy-induced hypertension.

    • J Rodríguez, J Cortiñas, M Bárcena, V Ginesta, and J Alvarez.
    • Servicio de Anestesiología y Reanimación, Hospital xeral de Galicia-Clínico Universitario, Facultad de Medicine, Universidad de Santiago, Santiago de Compostela, Spain.
    • Int J Obstet Anesth. 1995 Jan 1; 4 (1): 55-7.

    AbstractWe report one case of bradycardia and asystole immediately after the administration of 1 mg atropine and 2 mg neostigmine after the completion of an urgent caesarean section. We attribute this adverse reaction to the treatment of pregnancy-induced hypertension with methyldopa, perhaps facilitated by other drugs employed. Similar reactions have been reported relating to beta-receptor antagonists and tricyclic antidepressants, but not to methyldopa.

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