• J. Child Neurol. · Dec 2018

    Encephaloduroarteriosynangiosis for Pediatric Moyamoya Disease: A Single-Center Experience With 67 Cases in China.

    • Chengjun Wang, Meng Zhao, Jia Wang, Wang Shuo S 1 Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, PR China. , Dong Zhang, Kai Wang, and Jizong Zhao.
    • 1 Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, PR China.
    • J. Child Neurol. 2018 Dec 1; 33 (14): 901-908.

    AbstractThe purpose of this study is to investigate the surgical results and long-term outcomes of encephaloduroarteriosynangiosis for moyamoya disease in pediatric patients. We performed a retrospective analysis of 67 pediatric patients with moyamoya disease who underwent encephaloduroarteriosynangiosis in Beijing Tiantan Hospital. The case series included 36 boys and 31 girls. All the patients underwent surgical revascularization, and a total of 93 encephaloduroarteriosynangiosis procedures were performed (41 unilateral, 26 bilateral). The mean follow-up period after surgery was 30 months. During follow-up, ischemic stroke events were detected in 5 patients and the stroke rate for pediatric patients who underwent encephaloduroarteriosynangiosis procedure was 7.1% per patient-years. At the last follow-up, favorable outcomes (modified Rankin Scale score ≤ 2) were observed in 65 cases (97.0%). Our study suggests that long-term surgical outcome of encephaloduroarteriosynangiosis in pediatric moyamoya disease patients is satisfactory, and this technique has a positive impact on the prevention of stroke recurrence.

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