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- Deborah Y Booth, Joseph E Cruz, and Cynthia L Benson.
- Department of Pharmacy, Overlook Medical Center, Atlantic Health System, Summit, New Jersey.
- J Emerg Med. 2020 Jan 1; 58 (1): 110112110-112.
BackgroundTranexamic acid is an antifibrinolytic agent and functions as a competitive inhibitor of plasminogen activation, promoting hemostasis. Topical application of tranexamic acid for the control of epistaxis has been described in the literature, mainly through administration with gauze and packing. There is limited evidence for the use of tranexamic acid via alternative routes of administration such as nebulization.Case ReportWe describe a patient who presented to the emergency department with epistaxis who was treated with nebulized tranexamic acid. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: Our case provides an alternative treatment modality using nebulizing tranexamic acid to help manage epistaxis in patients that cannot be managed with topical antifibrinolytic therapy administered by other means.Copyright © 2019 Elsevier Inc. All rights reserved.
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