• Boohwi Hong, Sunyeul Lee, Yeojung Kim, Minhee Lee, Ann Misun Youn, Hyun Rhim, Seok-Hwan Hong, Yoon-Hee Kim, Seok-Hwa Yoon, and Chaeseong Lim.
• Department of Anesthesiology and Pain Medicine, Chungnam National University Hospital, 282 Munhwa-ro, Jung-gu, Daejeon, 35015, Republic of Korea.
• BMC Anesthesiol. 2019 Dec 18; 19 (1): 233.

BackgroundIntravenous anesthesia has been reported to have a favorable effect on the prognosis of cancer patients. This study was performed to analyze data regarding the relation between anesthetics and the prognosis of cancer patients in our hospital.MethodsThe medical records of patients who underwent surgical resection for gastric, lung, liver, colon, and breast cancer between January 2006 and December 2009 were reviewed. Depending on the type of anesthetic, it was divided into total intravenous anesthesia (TIVA) or volatile inhaled anesthesia (VIA) group. The 5-year overall survival outcomes were analyzed by log-rank test. Cox proportional hazards modeling was used for sensitivity.ResultsThe number of patients finally included in the comparison after propensity matching came to 729 in each group. The number of surviving patients at 5 years came to 660 (90.5%) in the TIVA and 673 (92.3%) in the VIA. The type of anesthetic did not affect the 5-year survival rate according to the log-rank test (P = 0.21). Variables associated with a significant increase in the hazard of death after multivariable analysis were male sex and metastasis at surgery.ConclusionsThere were no differences in 5-year overall survival between two groups in the cancer surgery.Trial RegistrationTrial registration: CRIS KCT0004101. Retrospectively registered 28 June 2019.

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