-
Randomized Controlled Trial Multicenter Study Clinical Trial
Repeated dosing of botulinum toxin type A for upper limb spasticity following stroke.
- M F Gordon, A Brashear, E Elovic, D Kassicieh, C Marciniak, J Liu, C Turkel, and BOTOX Poststroke Spasticity Study Group.
- North Shore/Long Island Jewish Health Systems, New Hyde Park, NY, USA. mfgordon@lij.edu
- Neurology. 2004 Nov 23; 63 (10): 1971-3.
AbstractThe authors evaluated the long-term efficacy and safety of botulinum toxin type A (BTX-A) in poststroke spasticity patients who completed a 12-week placebo-controlled study and received multiple open-label treatments with 200 to 240 U BTX-A for 42 weeks. Significant and sustained improvements were observed for Disability Assessment and Ashworth scores. Adverse events were generally mild. This extension of a double-blind study demonstrates that repeated treatments of BTX-A significantly improve function and tone in spasticity.
Notes
Knowledge, pearl, summary or comment to share?You can also include formatting, links, images and footnotes in your notes
- Simple formatting can be added to notes, such as
*italics*,_underline_or**bold**. - Superscript can be denoted by
<sup>text</sup>and subscript<sub>text</sub>. - Numbered or bulleted lists can be created using either numbered lines
1. 2. 3., hyphens-or asterisks*. - Links can be included with:
[my link to pubmed](http://pubmed.com) - Images can be included with:
 - For footnotes use
[^1](This is a footnote.)inline. - Or use an inline reference
[^1]to refer to a longer footnote elseweher in the document[^1]: This is a long footnote..