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Randomized Controlled Trial Clinical Trial
[Double blind randomized trial of metopimazine: for postoperative nausea and vomiting after cholecystectomy].
- C Rodary, A Elman, M Durand, J Cohen-Solal, and J N Maillard.
- Ann Anesthesiol Fr. 1979 Jan 1; 20 (2): 118-20.
AbstractEighty-four patients submitted to cholecystectomy were randomly assigned in a double-blind study either to an intravenous dose of 10 mg of metopimazine, three times D-1, for two days or to an identically administered placebo. A definite superiority of metopimazine as an anti-emetic drug was demonstrated. General acceptance was excellent, but arterial pressure might be looked over closely when metopimazine was administered intravenously immediately after a general anesthesia.
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