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          Randomized Controlled TrialImmediate effects of the combination of interferential therapy parameters on chronic low back pain: a randomized controlled trial.- Nicole Almeida, Luis Henrique Paladini, RacieleIvandra Guarda Korelo, Richard E Liebano, and Ana Carolina Brandt de Macedo.
- Department of Prevention and Rehabilitation in Physiotherapy, Universidade Federal do Paraná, Curitiba, Brazil.
- Pain Pract. 2020 Jul 1; 20 (6): 615-625.
 ObjectivesTo compare the immediate analgesic effects of 2 kHz or 4 kHz interferential current (IFC) with different amplitude-modulated frequencies (AMFs) (2 Hz or 100 Hz) on chronic low back pain (CLBP).DesignThree-arm double-blinded randomized controlled trial.SettingPrimary care.Participants175 patients (19 to 60 years of age, 105 female) with CLBP.InterventionsOne session of IFC: Interferential group (GI): GI2 kHz/100 Hz, GI2 kHz/2 Hz, GI4 kHz/100 Hz, GI4 kHz/2 Hz, or placebo.Main Outcomes MeasuresPain intensity by numerical rating scale of pain (NRS), McGill Pain Questionnaire (MPQ), and algometry.ResultsThere was a significant difference in NRS scores (P < 0.05) in the GI2 kHz/2 Hz, GI4 kHz/2 Hz, and GI4 kHz/100 Hz groups compared with those of the placebo group (PG), and a significant difference in MPQ scores in the GI4 kHz/2 Hz and GI4 kHz/100 Hz groups compared with those of the PG. In algometry, only the GI4 kHz/100 Hz group showed a significant difference (by 2 points in the lumbar region) compared with the PG. Of the carrier frequencies, an IFC of 4 kHz showed more effective results, although no significant difference was noted between the AMFs.ConclusionAn IFC with a carrier frequency of 4 kHz and an AMF of 100 Hz provide immediate analgesic effects in individuals with CLBP.Clinical Trial Registration NumberRBR-59YGRB.© 2020 World Institute of Pain. Notes
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