• Anaesth Intensive Care · Mar 2012

    Case Reports

    A persistent 'can't intubate, can't oxygenate' crisis despite rocuronium reversal with sugammadex.

    An interesting CICO case study highlighting that while sugammadex will rapidly and completely reverse paralysis, this is only one consideration when managing an airway crisis. The use of any reversal agent in an airway crisis should be considered within the context of the case and a clear understanding of the objective of our actions.

    Neuromuscular reversal will only improve a CICO scenario if spontaneous ventilation will improve patient oxygenation, otherwise return of muscle function may actually make other CICO interventions more difficult.

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    • B C Kyle, D Gaylard, and R H Riley.
    • Department of Anaesthesia and Pain Medicine, Royal Perth Hospital, Perth, Western Australia, Australia. bkyle@doctors.org.uk
    • Anaesth Intensive Care. 2012 Mar 1;40(2):344-6.

    AbstractA 'can't intubate, can't oxygenate' airway crisis is a rare event which most anaesthetists will never experience during their career(1,2). This report highlights the outcome of time-critical decisions in a potential airway catastrophe. Rocuronium was used as an alternative muscle relaxant for rapid sequence induction. The use of sugammadex in 'can't intubate, can't oxygenate' crises is discussed and highlights how, despite adequate reversal of neuromuscular blockade, the 'can't intubate, can't oxygenate' situation failed to resolve. An asymptomatic vallecular cyst was the causal factor in this scenario. Anaesthetic issues surrounding this pathology are discussed.

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    This article appears in the collection: Is sugammadex as good as we think?.

    Notes

    summary
    1

    An interesting CICO case study highlighting that while sugammadex will rapidly and completely reverse paralysis, this is only one consideration when managing an airway crisis. The use of any reversal agent in an airway crisis should be considered within the context of the case and a clear understanding of the objective of our actions.

    Neuromuscular reversal will only improve a CICO scenario if spontaneous ventilation will improve patient oxygenation, otherwise return of muscle function may actually make other CICO interventions more difficult.

    Daniel Jolley  Daniel Jolley
    pearl
    1

    Adequate reversal of neuromuscular blockade may not always be helpful when successfully managing a cannot intubate-cannot-ventilate crisis.

    Daniel Jolley  Daniel Jolley
    comment
    0

    Sugammadex is a great drug, but not a universal magic bullet.

    Daniel Jolley  Daniel Jolley

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