High-flow nasal cannula oxygenation utilization in

Eur. J. Intern. Med. · Jun 2019

Review

High-flow nasal cannula oxygenation utilization in respiratory failure.

High flow nasal cannula (HFNC) represents a new oxygenation system to be used in the treatment of respiratory emergencies. During HFNC therapy, the active humidification and air heating system allow the patient to tolerate higher flows by favouring physiologic mucociliary clearance and improving fluidity of respiratory secretions. ⋯ Several clinical trials in acute respiratory failure patients have suggested lower rate of invasive mechanical ventilation, improved comfort and enhanced survival by early HFNC utilization in comparison with conventional oxygen therapy (COT) or non-invasive ventilation (NIV). This review aims to summarize the main evidences on the use of HFNC in the acute setting and its major indications.

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- Andrea Boccatonda and Paolo Groff.
- Department of Internal Medicine, "G. d'Annunzio" University, Chieti, Italy. Electronic address: andrea.boccatonda@studenti.unich.it.
- Eur. J. Intern. Med. 2019 Jun 1; 64: 10-14.
AbstractHigh flow nasal cannula (HFNC) represents a new oxygenation system to be used in the treatment of respiratory emergencies. During HFNC therapy, the active humidification and air heating system allow the patient to tolerate higher flows by favouring physiologic mucociliary clearance and improving fluidity of respiratory secretions. Following this, FiO2 values are more stable and reliable, by reducing losses and minimizing ambient air entrainment. Several clinical trials in acute respiratory failure patients have suggested lower rate of invasive mechanical ventilation, improved comfort and enhanced survival by early HFNC utilization in comparison with conventional oxygen therapy (COT) or non-invasive ventilation (NIV). This review aims to summarize the main evidences on the use of HFNC in the acute setting and its major indications.Copyright © 2019 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.

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High-flow nasal cannula oxygenation utilization in respiratory failure.

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