• Eur. J. Intern. Med. · Dec 2019

    Multicenter Study

    Influence of the length of hospitalisation in post-discharge outcomes in patients with acute heart failure: Results of the LOHRCA study.

    • Òscar Miró, Joan Padrosa, Koji Takagi, Étienne Gayat, Víctor Gil, Pere Llorens, Francisco Javier Martín-Sánchez, Pablo Herrero-Puente, Javier Jacob, María Mir Montero, Josep Tost, Díez María Pilar López MPL Emergency Department, Hospital Universitario de Burgos, Burgos, Spain., Lissete Traveria, Raquel Torres-Gárate, María Isabel Alonso, Carmen Agüera, Amparo Valero, Patricia Javaloyes, W Frank Peacock, Héctor Bueno, Alexandre Mebazaa, ICA-SEMES Research Group, Marta Fuentes, Cristina Gil, Héctor Alonso, Pablo Garmila, García Guillermo Llopis GL Hospital Clínico San Carlos de Madrid,Spain., María Cecilia Yáñez-Palma, Sergio Iglesias López, Rosa Escoda, Carolina Xipell, Carolina Sánchez, Josep María Gaytan, María José Pérez-Durá, Eva Salvo, José Pavón, Antonio Noval, José Manuel Torres, María Luisa López-Grima, Marian Ángeles Juan, Alfons Aguirre, Julián Errasti Morales, Silvia Mínguez Masó, Francisco Ruiz, Franco José Miguel JM Hospital Miguel Servet de Zaragoza, Spain., Ana Belén Mecina, Susana Sánchez, Virginia Carbajosa, Pascual Piñera, Nicolás José Andrés Sánchez JAS Hospital Reina Sofía de Murcia, Spain., Raquel Torres Garate, Aitor Alquezar, Miguel Alberto Rizzi, Sergio Herrera, Alex Roset, Irene Cabello, Fernando Richard, Pérez José María Álvarez JMÁ Hospital Universitario de Burgos, Spain., Diez María Pilar López MPL Hospital Universitario de Burgos, Spain., Joaquín Vázquez Álvarez, García Belén Prieto BP Hospital Universitario Central de Asturias de Oviedo, Spain., María García García yMarta Sánchez González, Víctor Marquina, Inmaculada Jiménez, Néstor Hernández, Benjamín Brouzet, Sergio Ramos, Ana López, Juan Antonio Andueza, Rodolfo Romero, Martín Ruíz, Roberto Calvache, María Teresa Lorca, Luis Calderón, Beatriz Amores Arriaga, Beatriz Sierra, Mojarro Enrique Martín EM Hospital Sant Pau i Santa Tecla de Tarragona, Spain., Lisette Travería Bécquer, Guillermo Burillo, Lluís Llauger García, Gerard Corominas LaSalle, Carmen Agüera Urbano, Ana Belén García Soto, Elisa Delgado Padial, Ferrer Ester Soy ES Hospital Josep Trueta de Girona, Spain., Manuel Garrido, Francisco Javier Lucas, Rut Gaya, Carlos Bibiano, María Mir, Beatriz Rodríguez, Natalia Sánchez, José Luis Carballo, Esther Rodríguez-Adrada, and Belén Rodríguez.
    • Emergency Department, Hospital Clínic, Barcelona; "Emergencies: processes and pathologies" Research Group, IDIBAPS, University of Barcelona, Barcelona, Catalonia, Spain; The GREAT (Global REsearch in Acute Cardiovascular Conditions Team) Network, Rome, Italy. Electronic address: omiro@clinic.cat.
    • Eur. J. Intern. Med. 2019 Dec 1; 70: 24-32.

    ObjectiveTo investigate the relationship between length of hospitalisation (LOH) and post-discharge outcomes in acute heart failure (AHF) patients and to ascertain whether there are different patterns according to department of initial hospitalisation.MethodsConsecutive AHF patients hospitalised in 41 Spanish centres were grouped based on the LOH (<6/6-10/11-15/>15 days). Outcomes were defined as 90-day post-discharge all-cause mortality, AHF readmissions, and the combination of both. Hazard ratios (HRs), adjusted by chronic conditions and severity of decompensation, were calculated for groups with LOH >6 days vs. LOH <6 days (reference), and stratified by hospitalisation in cardiology, internal medicine, geriatrics, or short-stay units.ResultsWe included 8563 patients (mean age: 80 (SD = 10) years, 55.5% women), with a median LOH of 7 days (IQR 4-11): 2934 (34.3%) had a LOH <6 days, 3184 (37.2%) 6-10 days, 1287 (15.0%) 11-15 days, and 1158 (13.5%) >15 days. The 90-day post-discharge mortality was 11.4%, readmission 32.2%, and combined endpoint 37.4%. Mortality was increased by 36.5% (95%CI = 13.0-64.9) when LOH was 11-15 days, and by 72.0% (95%CI = 42.6-107.5) when >15 days. Conversely, no differences were found in readmission risk, and the combined endpoint only increased 21.6% (95%CI = 8.4-36.4) for LOH >15 days. Stratified analysis by hospitalisation departments rendered similar post-discharge outcomes, with all exhibiting increased mortality for LOH >15 days and no significant increments in readmission risk.ConclusionsShort hospitalisations are not associated with worse outcomes. While post-discharge readmissions are not affected by LOH, mortality risk increases as the LOH lengthens. These findings were similar across hospitalisation departments.Copyright © 2019 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.

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