Gastrointestinal endoscopy
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Gastrointest. Endosc. · Apr 2008
Randomized Controlled Trial Comparative StudyClinical efficacy of dexmedetomidine alone is less than propofol for conscious sedation during ERCP.
Propofol is an accepted method of sedation for an ERCP and generally achieves deep sedation rather than conscious sedation, and dexmedetomidine has sedative properties of equivalent efficacy. ⋯ Dexmedetomidine alone was not as effective as propofol combined with fentanyl for providing conscious sedation during an ERCP. Furthermore, dexmedetomidine was associated with greater hemodynamic instability and a prolonged recovery.