Journal of anesthesia history
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Biography Historical Article
A Nitrous-Oxide Pioneer Peddles His Own Dentifrice: "Dr Colton's Vegetable Dentonic".
During the latter half of the six-year long "Panic of 1873," nitrous-oxide pioneer G. Q. Colton developed, advertised, and sold his dentifrice, "Dr Colton's Vegetable Dentonic" to supplement his dental anesthetic enterprise.
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The aim of this study was to determine how interest in various general anesthetics among the authors of academic publications changed over the past 50 years. ⋯ The study revealed a constant decline over time in academic interest in the pharmacological basis of general anesthesia relative to all fields of anesthesia combined.
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Biography Historical Article
Charles T. Jackson and William T.G. Morton Patented the "Ethereal Solution of Opium" of Elton Romeo Smilie.
The Jackson-Morton 1846 patent for surgical insensibility by means of sulphuric ether states that opiates can be added to the ether and co-administered by inhalation. The erroneous concept that ether could carry opiates in its vapor phase at room temperature was proposed in Boston in 1846 by Elton Romeo Smilie (1819-1889), who believed that the opiates were more important than the ether vehicle.
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Historical Article
The Perfect and Famous Anesthetic Known as Methyl in Boston in 1895.
Extravagant claims were made for proprietary dental anesthetics in Boston, MA, in the late 1800s. For instance, in 1883, Urial K. Mayo introduced an inhaled Vegetable Anaesthetic comprised of nitrous oxide that had been uselessly pretreated with botanical material. ⋯ In 1895, the Dental Methyl Company advertised an agent they called Methyl, a supposedly perfect topical anesthetic for painless dental extraction. The active ingredient was probably chloroform. Anesthetic humbug did not cease in Boston on Ether Day of October 16, 1846.