Lancet neurology
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Meta Analysis
Clinical course of untreated cerebral cavernous malformations: a meta-analysis of individual patient data.
Cerebral cavernous malformations (CCMs) can cause symptomatic intracranial haemorrhage (ICH), but the estimated risks are imprecise and predictors remain uncertain. We aimed to obtain precise estimates and predictors of the risk of ICH during untreated follow-up in an individual patient data meta-analysis. ⋯ UK Medical Research Council, Chief Scientist Office of the Scottish Government, and UK Stroke Association.