Lancet neurology

The most recent articles from: Lancet Neurol February 2021

Lancet neurology · Feb 2021

Multicenter Study

The influence of timing of surgical decompression for acute spinal cord injury: a pooled analysis of individual patient data.

Although there is a strong biological rationale for early decompression of the injured spinal cord, the influence of the timing of surgical decompression for acute spinal cord injury (SCI) remains debated, with substantial variability in clinical practice. We aimed to objectively evaluate the effect of timing of decompressive surgery for acute SCI on long-term neurological outcomes. ⋯ None.

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Lancet neurology · Feb 2021

Randomized Controlled Trial Multicenter Study

Safety and efficacy of riluzole in patients undergoing decompressive surgery for degenerative cervical myelopathy (CSM-Protect): a multicentre, double-blind, placebo-controlled, randomised, phase 3 trial.

Degenerative cervical myelopathy represents the most common form of non-traumatic spinal cord injury. This trial investigated whether riluzole enhances outcomes in patients undergoing decompression surgery for degenerative cervical myelopathy. ⋯ AOSpine North America.

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