Respiratory physiology & neurobiology
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Respir Physiol Neurobiol · Feb 2014
Randomized Controlled TrialEffect of rostral fluid shift on pharyngeal resistance in men with and without obstructive sleep apnea.
Obstructive sleep apnea (OSA) relates to overnight rostral fluid shift, possibly because fluid accumulation around the pharynx increases pharyngeal resistance (Rph). We hypothesised that Rph will increase more in men with than without OSA in response to rostral fluid redistribution. ⋯ OSA patients have increased susceptibility to pharyngeal obstruction in response to rostral fluid redistribution, which could predispose to pharyngeal collapse during sleep.