Respiratory physiology & neurobiology
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Respir Physiol Neurobiol · Jun 2020
Randomized Controlled TrialNasal high flow improves ventilation during propofol sedation: A randomized cross-over study in healthy volunteers.
Hypoventilation and carbon dioxide (CO2) retention are common during sedation. The current study investigated the ventilation responses to nasal high flow (NHF) during sedation with propofol. ⋯ During sedation with propofol, NHF without supplemental oxygen attenuated CO2 retention and reduced the respiratory rate. The findings show that NHF can improve ventilation during sedation, which may reduce the risk of complications related to hypoventilation.