Ugeskrift for laeger
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Ugeskrift for laeger · Jun 2011
Review Comparative Study[Weight reducing and glucose reducing effects of liraglutide treatment for patients with type 2 diabetes].
Treatment with glucagon-like peptide-1 analogues including liraglutide is a new treatment option for patients with type 2 diabetes. Treatment with liraglutide decreases HbA1c by 1-2%, and additionally liraglutide has a reducing effect on weight, lipids and blood pressure. ⋯ The risk of major hypoglycaemic episodes is minimal. Long term data on treatment and adverse events with liraglutide are still lacking.
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Ugeskrift for laeger · Jun 2011
Review[Oxygen therapy in exercise-induced hypoxemia improves physical capacity and reduces dyspnea in patients with COPD].
Many chronic obstructive pulmonary disease patients suffer from dyspnoea and reduced physical abilities. Some of the patients exhibit desaturation during physical exercise. ⋯ Yet it is not possible to draw a clear conclusion regarding the effects of more prolonged (weeks) treatment. The studies are in general small and of poor methodological quality.
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Effective palliative care requires continuous contact, exchange of information, and mutual professional respect between all the relevant health-care professionals. At least one of the professionals should coordinate care. Many patients with advanced cancer report uncovered palliative care needs. In order to assure that all cancer patients receive optimal palliative care, earlier initiation and better integration of basic palliative care (at hospitals and in primary care) and specialist palliative care teams are needed.
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A checklist is a cognitive tool specifying the actions necessary to complete a given task. It serves to improve the quality of care, support the memory of the user and it may serve to indicate the necessary communicative steps within a team. ⋯ Preliminary results indicate a potential for patient safety. However, no evidence indicates that a checklist in itself is sufficient to obtain clinical results: training and motivating staff, supporting implementation, and conducting follow-up and evaluation are as important as the checklist itself to achieve results.
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Ugeskrift for laeger · Jun 2011
[Infections related to central venous catheters in children affected from malignant diseases].
Central venous catheters (CVC) are an essential part of the treatment of children with haematological and oncological diseases. Unfortunately, CVC also represent a major risk factor of bloodstream infections. ⋯ On suspicion of CRBSI empirical antibiotic treatment with piperacillin-tazobactam, meropenem or ampicillin in combination with gentamicin is recommended. The systemic treatment can be combined with catheter-lock therapy.