African health sciences
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African health sciences · Mar 2017
In vitro investigation of clofazimine analogues for antiplasmodial, cytotoxic and pro-oxidative activities.
Tetramethyl-piperidine-substituted, B4119 and B4158 have been shown to exhibit antiplasmodial activity. ⋯ Tetramethylpiperidyl-subsituted phenazines may potentially be useful antimalarial/antitumor agents with no pro-oxidative properties. In vivo studies on the agents relative to these properties are recommended.
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African health sciences · Mar 2017
Comparative StudyLateral retroperitoneoscopic adrenalectomy for complicated adrenal tumor larger than 5 centimeters.
The role of lateral retroperitoneoscopic adrenalectomy (LRA) for complicated tumor with large diameter remains controversial, this study aimed to evaluate the effectiveness of this procedure on the management of tumor larger than 5cm in diameter. ⋯ Our study shows that LRA can be performed safely and effectively for complicated adrenal tumors larger than 5 cm in diameter, but it remains technically demanding.