African health sciences
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African health sciences · Dec 2019
Randomized Controlled Trial Comparative StudyEffect of target controlled propofol infusion versus intermittent boluses during oesophagogastroduodenoscopy: a randomized controlled trial.
Propofol is administered as intermittent boluses to achieve deep sedation to facilitate oesophagogastroduodenoscopy. Target controlled infusion (TCI) can be employed for this purpose. ⋯ TCI of propofol was associated with fewer episodes of hypoxia compared to intermittent bolus administration. Similar hemodynamic profiles and comparable time to recovery were demonstrated by these two sedation techniques.
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African health sciences · Dec 2019
Randomized Controlled Trial Comparative StudyIntra-operative low-dose ketamine does not reduce the cost of post-operative pain management after surgery: a randomized controlled trial in a low-income country.
In developing countries, post-operative pain remains underestimated and undertreated due to economic constraints, lack of awareness and limited resources. In contrast, ketamine is an effective, readily available, easy to use and inexpensive drug frequently used in poor settings. ⋯ Our results do not support the utilization of intra-operative low dose ketamine as a cost-saving post-operative pain treatment strategy for all types of surgery in low-resource settings.
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African health sciences · Dec 2019
Randomized Controlled TrialEffect of removal of AuraOnce™ laryngeal mask in awake or deep anaesthesia: a randomized controlled trial.
The manufacturer Ambu® recommends that the AuraOnce™ laryngeal mask be removed once the patient is fully awake. Studies have shown benefit in removal of the laryngeal mask airway while a patient is deeply anaesthetized. Current evidence is inconclusive, as to which approach is preferable and safer in adults. ⋯ The removal of the AuraOnce™ laryngeal mask while the patient is still deeply anaesthetised is not as safe as or safer than awake removal.