African health sciences
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African health sciences · Jun 2023
Meta AnalysisGarlic supplementation for the treatment of chronic liver disease: a meta-analysis of randomized controlled trials.
The efficacy of garlic supplementation for chronic liver disease remains controversial. We conduct a meta-analysis to explore the influence of garlic supplementation versus placebo on the treatment of chronic liver disease. ⋯ Garlic supplementation is effective to treat chronic liver disease.
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African health sciences · Jun 2023
Meta AnalysisTherapeutic outcome of dapagliflozin in patients with type 2 diabetes and non-alcoholic fatty liver disease: a meta-analysis of randomized controlled trials.
The efficacy of dapagliflozin remains controversial for patients with type 2 diabetes and non-alcoholic fatty liver disease. We conduct this meta-analysis to explore the influence of dapagliflozin versus placebo on the treatment efficacy of type 2 diabetes complicated with non-alcoholic fatty liver disease. ⋯ Dapagliflozin benefits to improve hepatic function and glucose control in patients with type 2 diabetes and non-alcoholic fatty liver disease, as evidenced by the reduction in ALT, AST, fasting glucose and HbA1c.
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African health sciences · Jun 2023
Meta AnalysisBoosting COVID-19 vaccine inoculation and booster shots: a systematic review and meta-analysis of factors that influence Coronavirus vaccine uptake in practice.
Vaccines alone do not control pandemics, but vaccinations. The hope of COVID-19 pandemic control is hinged on vaccinations and other public health measures. This systematic review/meta-analysis (SR/MA) investigated the factors that inform coronavirus vaccine uptake globally in an attempt to improve COVID-19 immunization. ⋯ Wanning and acquaintance's vaccination status as factors to vaccination are insights the present paper is bringing to the limelight. Health promotion and COVID-19 vaccination planning are crucial for enhancing vaccine uptake.
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African health sciences · Jun 2023
Meta AnalysisEmricasan for the treatment of liver cirrhosis: a meta-analysis of randomized controlled trials.
The efficacy of emricasan for liver cirrhosis remains controversial. We conduct a systematic review and meta-analysis to explore the influence of emricasan versus placebo on the treatment of liver cirrhosis. ⋯ Emricasan treatment provided no benefit for the treatment of liver cirrhosis.
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African health sciences · Jun 2023
Meta AnalysisAssociation between interleukin-12 +1188A/C polymorphism and the risk of tuberculosis: A meta-analysis.
The role of interleukin-12(IL-12) gene +1188A/C polymorphism has been indicated in the progression of tuberculosis (TB). Nevertheless, the outcomes remain controversial. ⋯ The present findings indicated that IL-12 +1188A/C polymorphism was not related to the risk of TB.