African health sciences
-
African health sciences · Dec 2023
ReviewMaternal inherited thrombophilia and recurrent pregnancy loss: a Tunisian study and review of literature.
Inherited thrombophilia, mainly the Factor V Leiden (FVL) and Prothrombin mutation (PTM) are the most risk factors for venous thrombosis especially during pregnancy and was strongly associated with recurrent pregnancy loss (RPL), a devastating reproductive problem that affects more than 1% of couples who are trying to conceive. The frequencies also the correlation among these polymorphisms and RPL have been reported controversially in various populations. ⋯ This study emphasizes the importance of testing for FVL and FIIM in women with RPL; mainly in the context of thrombotic events. Multi-center collaboration is necessary to clarify the real impact of thrombotic molecular defects on the pregnancy outcome, to ascertain the effect of inherited thrombophilia on recurrent pregnancy loss and then to evaluate the appropriate therapeutic approach.
-
African health sciences · Dec 2023
Prevalence, pattern and determinants of substance abuse among youths in a rural community of Osun State, Southwest Nigeria.
This study assessed the prevalence, patterns and factors associated with substance abuse among youths of Ejigbo community, Osun State, Nigeria. ⋯ Respondents in the current study had good knowledge, predominantly negative attitude but a relatively high burden of substance abuse. There is urgent need for policy makers to upscale fights against the menace of substance abuse among rural Nigerian youths.
-
African health sciences · Dec 2023
Meta AnalysisMight the fungus candida albicans a risk factor for autism? A meta-analysis study.
Due to the high increase in rate of autism, it has gained great importance to determine the etiology of autism spectrum disorder. The purpose of our study was to assess the role of Candida albicans as a risk factor to cause autism behavior. ⋯ This study as a whole showed that children diagnosed with autism spectrum disorder have higher frequency of the presence of the fungus Candida albicans. Therefore, Candida albicans may be an etiological factor for the autistic behavior in children.
-
African health sciences · Dec 2023
Randomized Controlled TrialFrequency of red blood cell allo-immunization in patients undergoing blood transfusion at the Uganda Cancer Institute.
There is limited data on red blood cell (RBC) alloimmunization in patients with cancer in sub-Saharan Africa (SSA). We examined the frequency of RBC alloimmunization in transfused patients with cancers in Uganda. ⋯ There was no RBC alloimmunization in participants with cancers. Routine RBC allo-antibody screening in all patients with cancer in SSA requires further research.
-
African health sciences · Dec 2023
Frequency of domestic violence in pregnancy and its adverse maternal outcomes among Pakistani women.
To determine the frequency of domestic violence in pregnancy and its adverse maternal outcomes among Pakistani women. ⋯ Our study shows that high frequency of violence at the time of pregnancy is related to negative maternal outcomes. Women should be screened for violence and support services for such women should be provided in the country.