African health sciences
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African health sciences · Dec 2023
Meta AnalysisA systemic review and meta-analysis on the prevalence and associated factors of hypertension among adult clients in Ethiopia.
Hypertension is a major risk factor for premature mortality and excessive morbidity in the world. It is a growing public health problem in developing countries including Ethiopia. It is a silent killer. Information on the prevalence of hypertension and its associated factors is to be considered vital to focus on early diagnosis and improve prevention and control of cardiovascular diseases. However, on the prevalence and contributing factors of hypertension in Ethiopia, there is a dearth of information. Thus, this review aimed to estimate the pooled prevalence of hypertension and its contributing factors among Ethiopia's adult population. ⋯ The prevalence of hypertension among the adult population in Ethiopia is high. Healthcare professionals and other stakeholders should give attention to the early detection of hypertension in Ethiopia to reduce the burden of the disorder.
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African health sciences · Dec 2023
ReviewA review of fermented milks: potential beneficial effects on human nutrition and health.
Fermented dairy products are formed during the acidification of milk through fermentation by suitable microorganisms; it contains different microorganisms in sufficient numbers and in an active state. A wide range of fermented milk products are produced and consumed around the world, including yogurt, kefir, koumiss, and yogurt beverages. There are various health benefits associated with the consumption of fermented dairy. ⋯ In addition to these effects, it has many other beneficial effects such as positive effects on type 2 diabetes and hypertension, antimutagen and antioxidant effects, and reduction of allergic symptoms. Dairy products including fermented milk are known to be the main carrier of probiotic microorganisms, and many clinical studies show the effects of probiotic strains on health. In this study, the effects of fermented milks on human nutrition and health are mentioned.
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African health sciences · Dec 2023
ReviewIsoniazid hair drug levels among TB patients as a tool to monitor adherence, exposure, and TB treatment outcomes and its acceptability in a multicultural setting. A narrative review.
Accumulation of chemicals including drugs in hair has been used in forensic investigations. Studies have reported isoniazid drug levels in the hair of TB patients. ⋯ Literature on Isoniazid hair drug levels among TB patients as a tool to monitor adherence, exposure, and TB treatment outcomes, and its acceptability is limited and more research is needed.
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African health sciences · Dec 2023
ReviewMaternal inherited thrombophilia and recurrent pregnancy loss: a Tunisian study and review of literature.
Inherited thrombophilia, mainly the Factor V Leiden (FVL) and Prothrombin mutation (PTM) are the most risk factors for venous thrombosis especially during pregnancy and was strongly associated with recurrent pregnancy loss (RPL), a devastating reproductive problem that affects more than 1% of couples who are trying to conceive. The frequencies also the correlation among these polymorphisms and RPL have been reported controversially in various populations. ⋯ This study emphasizes the importance of testing for FVL and FIIM in women with RPL; mainly in the context of thrombotic events. Multi-center collaboration is necessary to clarify the real impact of thrombotic molecular defects on the pregnancy outcome, to ascertain the effect of inherited thrombophilia on recurrent pregnancy loss and then to evaluate the appropriate therapeutic approach.
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African health sciences · Sep 2023
ReviewA 5-year review of research ethics applications in a tertiary health and educational institution in Nigeria.
African contribution to global research output is said to be low. Poor funding and poor skills in grant writing have been suggested as important factors for this situation. ⋯ Local studies formed the bulk of the submissions for ethics clearance. National and international donor funding of research is abysmally low in this Nigerian tertiary institution studied.