African health sciences
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African health sciences · Sep 2013
Randomized Controlled TrialEffect of wound infiltration with bupivacaine on pulmonary function after elective lower abdominal operations.
Subcutaneous or intrafascial wound infiltration of local anaesthetic with systemic opioids has been shown to enhance patient comfort with improved analgesia and reduced opioid requirements. ⋯ Bupivacaine wound infiltration produced statistically significant elevations in pulmonary function tests results at all assessment periods.
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African health sciences · Sep 2013
Randomized Controlled TrialImpact of weight loss on markers of systemic inflammation in obese Saudi children with asthma.
Weight loss studies were conducted in children without asthma have demonstrated a reduction in systemic inflammation. However, the impact of weight loss in the obese paediatric population with asthma has not been investigated. ⋯ Weight loss improves markers of systemic inflammation in obese Saudi children with bronchial asthma.
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African health sciences · Jun 2013
Randomized Controlled TrialAntiemetic effects of dexamethasone and ondansetron combination during cesarean sections under spinal anaesthesia.
Nausea and vomiting are frequently seen in patients undergoing cesarean section (CS) under regional anesthesia. We aimed to compare the antiemetic efficacy of ondansetron and dexamethasone combination with that of the use of each agent alone to decrease the incidence of post-delivery intraoperative nausea and vomiting (IONV) during CS under spinal anesthesia. ⋯ Single dose 4mg ondansetron, 8mg dexamethasone, or combined use of 8mg dexamethasone+4mg ondansetron, given intravenously is all effective agents for the control of postdelivery IONV. Combined use of dexamethasone and ondansetron for the same indication does not seem to increase the antiemetic efficacy.
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African health sciences · Jun 2012
Randomized Controlled TrialEffect of vitamin A adjunct therapy for cerebral malaria in children admitted to Mulago hospital: a randomized controlled trial.
Malaria is a leading cause of mortality in Uganda accounting for 25% of deaths among children. Hitherto no adjunct therapy has been identified to improve outcome of cerebral malaria. Retinol suppresses growth of P.falciparum, scavenges free radicals, and exhibits synergistic action with quinine in parasite clearance. ⋯ Vitamin A as adjunct therapy did not significantly reduce coma duration but there were fewer deaths in the vitamin A arm.
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African health sciences · Dec 2009
Randomized Controlled TrialErgogenic effect of varied doses of coffee-caffeine on maximal aerobic power of young African subjects.
Caffeine one of the readily available stimulants consumed daily by more than 80% of the world's population, making it the most widely consumed drug in history. The objective of this study was to determine the effects of different doses (5, 10 &15 mg.kg(-1)) of caffeine per kilogram body weight on maximal aerobic power of normal young black African (Nigerian) male adults. ⋯ It was concluded that caffeine dose of up to 15mg/kg seems not to have any ergogenic effect on maximum aerobic power of young black African male adults.