African health sciences
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African health sciences · Dec 2017
Mammographic classification of breast lesions amongst women in Enugu, South East Nigeria.
The study was to classify lesions identified on mammograms using Breast Imaging Reporting and Data System (BIRADS) grading method. This was in view of ascertaining the rate of occurrence of breast malignancy of the studied population. ⋯ Classification of breast lesion using BI-RADS grading system is a veritable tool in the diagnosis of the breast lesion. The present study shows that 3.6% of the population has a high index of malignancy.
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African health sciences · Dec 2017
The effect of interrupted anti-retroviral treatment on the reconstitution of memory and naive T cells during tuberculosis treatment in HIV patients with active pulmonary tuberculosis.
The reconstitution of cellular immune components contributes to clinical outcome of HIV and Mycobacterium tuberculosis (MTB) infection. Interruption of anti-retroviral therapy (ART) could lead to perturbations in reconstitution of T cells in HIV/ tuberculosis (TB) patients. ⋯ Interrupting ART alters CD8+ but not CD4+ sub-sets in patients with less advanced HIV infection and TB.
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African health sciences · Dec 2017
Sub-clinical middle ear malfunctions in elderly patients; prevalence, pattern and predictors.
Little is known about functioning of the middle ear with advancing age. ⋯ 21.5% of elderly Africans had subclinical abnormalities in their middle ear functioning, mostly with type AS tympanogram. Independent clinical predictors of S-MEM included previous head injury, diabetes, history of osteoarthritis of knee joints, and absent acoustic reflex.
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African health sciences · Dec 2017
The market dynamics of selective serotonin re-uptake inhibitors: a private sector study in South Africa.
The objective of this study was to analyse the market share of generic vs originator selective serotonin re-uptake inhibitors (SSRIs), and also compare market share of different SSRIs in the private health care sector in South Africa, over a period of 4 years. ⋯ In line with policies, generic SSRIs hold a larger volume of the market in the private sector in South Africa.
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African health sciences · Dec 2017
Analysis of SNPs of MC4R, GNB3 and FTO gene polymorphism in obese Saudi subjects.
The goal of this study was to analyze the association between the FTO rs17817449 (G>T), G protein beta3 subunit (GNB3) C825T and Melanocortin 4 receptor (MC4R) A822G single nucleotide polymorphism (SNP) with obesity in Saudi subjects. ⋯ The polymorphism of FTO gene rs17817449 and GNB3 gene rs5443 (C825T) may be a genetic determinant of obesity in Saudi population whereas impact of MC4R Asn274Ser change could not be detected.