Nephron. Physiology
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Nephron. Physiology · Jan 2007
Randomized Controlled Trial Comparative StudyFrusemide administration in critically ill patients by continuous compared to bolus therapy.
Frusemide is frequently administered to critically ill patients in the intensive care unit (ICU). We investigated whether continuous frusemide infusion therapy was more effective than regular intermittent bolus doses at causing diuresis. ⋯ Both intermittent boluses and continuous infusion of frusemide were successful in achieving algorithm-driven diuresis. However, continuous infusion therapy was more effective than intermittent boluses since the dose of frusemide required was significantly less.