Medicina clinica
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Meta Analysis
Chronic thromboembolic pulmonary hypertension treatment and sex: Systematic review and meta-analysis.
Chronic thromboembolic pulmonary hypertension (CTEPH) is a complication of pulmonary embolism and a major cause of chronic pulmonary hypertension leading to right heart failure and death. While pulmonary endarterectomy is the treatment of choice, some patients might benefit from medical therapy or balloon pulmonary angioplasty. Sex differences in outcomes of these therapies are not well characterized. ⋯ Women and men might show different hemodynamic responses to riociguat or BPA for CTEPH.
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Inmunocompromised people have higher SARS-CoV-2 morbi-mortality and they are subsidiary to receive pre-exposure prophylaxis. The objective of this study is to evaluate the effectiveness of tixagevimab/cilgavimab (Evusheld) in preventing SARS-CoV-2 infections, hospitalizations and mortality in immunocompromised patients. ⋯ This study demonstrates that Evusheld reduces the SARS-CoV-2 infections.