Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
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Clin. Gastroenterol. Hepatol. · Oct 2009
Randomized Controlled Trial Comparative StudyA randomized controlled trial of enemas in combination with oral laxative therapy for children with chronic constipation.
After 5 years of intensive oral laxative use, up to 30% of constipated children still have an unsuccessful outcome. Children refractory to oral laxatives might benefit from regular rectal evacuation by enemas. This randomized controlled trial compared the effects of additional treatment with rectal enemas (intervention) with conventional treatment alone (oral laxatives, control) in severely constipated children. ⋯ There is no additional effect of enemas compared with oral laxatives alone as maintenance therapy for severely constipated children.