Expert opinion on drug safety
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Expert Opin Drug Saf
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Expert Opin Drug Saf · Dec 2016
Multicenter StudySeverity of statin-induced adverse effects on muscle and associated conditions: data from the DAMA study.
Statins are generally well tolerated, but muscular adverse effects appear to be the most common obstacle limiting their use. Our objective was to describe the severity of muscle injury (myalgia, myositis and rhabdomyolysis) and associated conditions related to statin therapy that may be clinically significant. ⋯ Myalgia was the most common muscle adverse effect associated with statin therapy. Excessive alcohol consumption and pravastatin were independently associated with myositis or rhabdomyolysis.