Chemotherapy
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Randomized Controlled Trial Multicenter Study
Prulifloxacin versus levofloxacin in the treatment of respiratory and urinary tract infections: a multicentre, double-blind, randomized controlled clinical trial.
Prulifloxacin is a promising fluoroquinolone antibiotic. A multicentre, double-blind, randomized clinical study was designed to evaluate its efficacy and safety compared to that of levofloxacin for the treatment of respiratory and urinary infections of Chinese patients. ⋯ Prulifloxacin is as effective and well tolerated as levofloxacin in the treatment of respiratory and urinary tract infections.
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Randomized Controlled Trial Comparative Study
Clinical studies on the treatment of cancer cachexia with megestrol acetate plus thalidomide.
The management of cancer-related anorexia/cachexia syndrome (CACS) is a great challenge in clinical practice. To date, practice guidelines for the prevention and treatment of CACS are lacking. The authors conducted a randomized study to confirm the effectiveness and safety of treatment of CACS utilizing megestrol acetate (MA) plus thalidomide. ⋯ A combination regimen of MA and thalidomide is more effective than MA alone in the treatment of CACS.