Revista da Associacao Medica Brasileira (1992)
-
Rev Assoc Med Bras (1992) · May 2020
Practice Guideline Meta AnalysisAdvanced melanoma in adults: Pembrolizumab as a treatment option.
The Guidelines Project, an initiative of the Brazilian Medical Association, aims to combine information from the medical field in order to standardize producers to assist the reasoning and decision-making of doctors. The information provided through this project must be assessed and criticized by the physician responsible for the conduct that will be adopted, depending on the conditions and the clinical status of each patient.
-
Rev Assoc Med Bras (1992) · May 2020
Impact of intermittent fasting on body weight in overweight and obese individuals.
To verify the relationship of intermittent fasting in the bodyweight of overweight and obese individuals through a systematic literature review. ⋯ Results did not provide evidence of the effect of intermittent fasting on weight loss in overweight or obese individuals.
-
Rev Assoc Med Bras (1992) · May 2020
Review Case ReportsEctopic ureter associated with Zinner's syndrome in a kidney recipient: case report and literature review.
INTRODUCTION Zinner's Syndrome is a triad of mesonephric duct anomalies comprising unilateral renal agenesis, seminal vesicle cyst, and ejaculatory duct obstruction. In this study, we present a kidney recipient with ectopic ureter associated with Zinner's syndrome and a literature review. CASE PRESENTATION A 59-year-old male with a history of chronic kidney disease and left renal agenesis underwent deceased donor kidney transplantation. ⋯ DISCUSSION AND CONCLUSION Congenital seminal vesicle disorders are usually associated with ipsilateral urinary duct anomalies stemming from the same embryonic structure. To our knowledge, this is the first case report that describes kidney transplantation in a patient with ipsilateral renal agenesis and ectopic ureter ending in the seminal vesicle cyst. In patients with renal agenesis, during the ipsilateral urinary tract anastomosis, the possibility of ectopic ureter should be kept in mind otherwise graft loss can occur with a high morbidity rate.
-
Rev Assoc Med Bras (1992) · May 2020
Immunological aspects of coronavirus disease during pregnancy: an integrative review.
OBJECTIVE To review the immunological aspects of the 2019 coronavirus disease (COVID-19) in pregnancy, based on the scientific evidence currently available. METHODS An integrative review was performed by two independent researchers, based on the literature available in the MEDLINE (via PubMed) and LILACS databases, using the descriptors "pregnancy" and "COVID-19". This search included articles published up until 14th April 2020 published in English, Spanish or Portuguese. ⋯ Therefore, pregnant women may represent a vulnerable group to COVID-19 infection, primarily due to the immune imbalance in the maternal-fetal interface. CONCLUSION Maternal immune response probably plays an important role in the pathophysiology of this infection, although some details remain unsolved. Although further studies are needed to deeply investigate the immunological aspects of the disease in pregnancy, our findings may provide insights into the possible immune mechanisms involved in the pathophysiology of COVID-19 in pregnancy.