Revista da Associacao Medica Brasileira (1992)
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Rev Assoc Med Bras (1992) · Jan 2024
Effect of Ki-67 proliferation index on survival in large cell neuroendocrine carcinoma of the lung.
Large cell neuroendocrine carcinoma of the lung is a rare type of lung cancer. There is a limited number of studies on clinical and histopathological characteristics that are effective in survival. The aim of this study was to investigate the relationship between histopathological and clinical characteristics, mainly Ki-67 proliferation index, and survival in patients diagnosed with large cell neuroendocrine carcinoma of the lung. ⋯ Our study identified subgroups with decreased survival in large cell neuroendocrine carcinoma of lung patients. Studies including a larger number of patients are needed to identify the prognostic importance of these clinical and histopathological characteristics.
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Rev Assoc Med Bras (1992) · Jan 2024
Levosimendan: efficacy and safety in pediatric heart failure treatment.
The objective of this study was to assess the effectiveness and safety of levosimendan as an alternative treatment for pediatric patients with decompensated heart failure unresponsive to conventional inotropes and to emphasize its role in enhancing cardiovascular stability. ⋯ Levosimendan demonstrates its significance in managing pediatric heart failure, indicating its safety and potential to enhance cardiac outcomes by reducing reliance on traditional inotropes.
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As healthy microbiota lays the foundation, it is crucial for midwives, who play an important role and responsibility in providing necessary recommendations for strengthening the connection between the mother and the child, to understand the basic structures and functions of various microbial communities and to be knowledgeable about microbiota and health. Therefore, this study aimed to provide microbiota education to midwifery students to explain the importance of microbiota for health, demonstrate its relationship with newborn health, women's health, and diseases, and evaluate the students' awareness of microbiota at the end of the education. ⋯ Through peer education, areas of confusion experienced by students regarding microbiota were gamified, resolved through mutual knowledge exchange, and awareness of microbiota was raised.