Revista da Associacao Medica Brasileira (1992)
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Rev Assoc Med Bras (1992) · Jan 2024
Meta AnalysisNatural supplementation to effectively treat cancer-induced fatigue: evidence of a meta-analysis on the use of guaraná.
Cancer-related fatigue is a pervasive symptom, affecting up to 90% of cancer patients throughout their illness, and can persist well after treatment has ended. Despite its prevalence, no definitive evidence-based treatment exists, leading to an abundance of proposed alternatives, including natural supplements. To further explore the potential effects of guaraná on cancer-related fatigue, a systematic review with meta-analysis was conducted and registered on the International Prospective Register of Systematic Reviews (CRD42023484144). ⋯ This meta-analysis provides support for the use of guaraná in the treatment of cancer-related fatigue. However, further investigation through larger prospective randomized controlled trials is necessary to validate these findings.
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Rev Assoc Med Bras (1992) · Jan 2024
Review Meta Analysis Comparative StudyOnline hemodiafiltration vs. high-flux hemodialysis in end-stage renal disease: a meta-analysis.
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Rev Assoc Med Bras (1992) · Jan 2024
Meta AnalysisConclusions of clinical trials assessing monoclonal antibodies and sponsored by pharmaceutical industry: a meta-research study.
The objective of this study was to describe and critically appraise the conclusions of randomized clinical trials assessing monoclonal antibodies sponsored by the pharmaceutical industry. ⋯ Most of the included randomized clinical trials on monoclonal antibodies funded by the industry concluded a drug-favorable direction of effect. Recommendations for practice were common, while recognition of uncertainty and statements regarding the need for future studies were less frequently present in the conclusion.