Revista da Associacao Medica Brasileira (1992)
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Rev Assoc Med Bras (1992) · Oct 2016
Interest in research among medical students: Challenges for the undergraduate education.
In recent decades, there has been a reduction in the number of graduates from medical schools who choose to pursue a career in scientific research. That has an impact on the profile of graduates, since medical education depends on understanding the formation of scientific evidence. The construction of new knowledge is also hampered by the reduction of medical scientists, whose clinical experience with patients provides an essential step towards medical Science evolution. ⋯ Although interest in research is clearly present among the students, this is still an underexplored element among the population studied. The incorporation of research in the learning process depends on stimulus and guidance until it becomes culturally consolidated as an essential element of the medical training.
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Rev Assoc Med Bras (1992) · Oct 2016
Wake-up stroke: Clinical characteristics, sedentary lifestyle, and daytime sleepiness.
Wake-up stroke (WUS) is defined when the exact time of the beginning of the symptoms cannot be determined, for the deficits are perceived upon awakening. Sleep alterations are important risk factors for stroke and cardiovascular diseases. This study evaluates the characteristics of patients with and without WUS, the presence of daytime sleepiness, and associated risk factors. ⋯ Wake-up stroke occurs in approximately 25% of stroke cases. In this study, patients with WUS had more diabetes and sedentary lifestyle. Daytime sleepiness is frequent and is associated with sedentary lifestyle and heavy drinking.
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Rev Assoc Med Bras (1992) · Oct 2016
Mobilization of hematopoietic progenitor cells for autologous transportation: consensus recommendations.
Selected patients with certain hematological malignancies and solid tumors have the potential to achieve long-term survival with autologous hematopoietic progenitor cell transplant. The collection of these cells in peripheral blood avoids multiple bone marrow aspirations, results in faster engraftment and allows treatment of patients with infection, fibrosis, or bone marrow hypocellularity. However, for the procedure to be successful, it is essential to mobilize a sufficient number of progenitor cells from the bone marrow into the blood circulation. Therefore, a group of Brazilian experts met in order to develop recommendations for mobilization strategies adapted to the reality of the Brazilian national health system, which could help minimize the risk of failure, reduce toxicity and improve the allocation of financial resources.
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Rev Assoc Med Bras (1992) · Oct 2016
Application of prognostic score IPSET-thrombosis in patients with essential thrombocythemia of a Brazilian public service.
In patients with essential thrombocythemia (ET), the vascular complications contribute to morbidity and mortality. To better predict the occurrence of thrombotic events, an International Prognostic Score for Thrombosis in Essential Thrombocythemia (IPSET-thrombosis) has recently been proposed. We present the application of this score and compare its results with the usual classification system. ⋯ Cardiovascular risk factors and leukocytosis were directly associated with arterial thrombosis. IPSET-thrombosis appears to be better than the traditional classification at identifying lower risk patients who do not need specific therapy.
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Rev Assoc Med Bras (1992) · Oct 2016
Outcomes of allogeneic stem cell transplantation among patients with acute myeloid leukemia presenting active disease: Experience of a single European Comprehensive Cancer Center.
Allogeneic hematopoietic stem cell transplantation (ASCT) representes a potentially curative approach for patients with relapsed or refractory acute myeloid leukemia (AML). We report the outcome of relapsed/refractory AML patients treated with ASCT. ⋯ In our cohort, TRM in first years after ASCT remains considerable, but ASCT in this setting seems to be a good choice for AML patients with active disease. However, novel approaches are needed to reduce TRM and relapse in this set of patients.