Revista da Associacao Medica Brasileira (1992)
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Rev Assoc Med Bras (1992) · Nov 2016
Psychometric properties of the Brazilian version of the Personal Experience Screening Questionnaire.
The Personal Experience Screening Questionnaire (PESQ) is an instrument devised for assessing the magnitude of drug misuse among adolescents. However, its psychometric properties have not been evaluated in adolescent samples outside the United States. ⋯ Evidence to support the reliability and validity of the Brazilian version of the Personal Experience Questionnaire was found.
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Rev Assoc Med Bras (1992) · Nov 2016
Observational StudyImpact of shoe size in a sample of elderly individuals.
The use of an improper shoe size is common in older people and is believed to have a detrimental effect on the quality of life related to foot health. The objective is to describe and compare, in a sample of participants, the impact of shoes that fit properly or improperly, as well as analyze the scores related to foot health and health overall. ⋯ Inadequate shoe size has a significant negative impact on quality of life related to foot health. The degree of negative impact seems to be associated with age, sex, and body mass index (BMI).
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Rev Assoc Med Bras (1992) · Nov 2016
Observational StudyAdvanced dementia in a sample of Brazilian elderly: Sociodemographic and morbidity analysis.
To investigate the sociodemographic and morbidity profile of advanced dementia patients and sociodemographic data of their primary caregivers. ⋯ Patients with advanced dementia present a high morbidity profile, low income, and depend on the care given by family members, mostly unemployed daughters.
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Rev Assoc Med Bras (1992) · Nov 2016
Worse prognosis in breast cancer patients can be predicted by immunohistochemical analysis of positive MMP-2 and negative estrogen and progesterone receptors.
Breast cancer is the most cause of death, and approximately 90% of these deaths are due to metastases. Matrix metalloproteinase-2 (MMP-2) gelatinase activity is able to degrade a major constituent of the tumor microenvironment, type IV collagen. Two well-established proteins used as markers in clinical practice for breast cancer are the receptors for estrogen (ER) and progesterone (PR). Although the presence of these receptors has been associated with a better prognosis, loss of these proteins can occur during tumor progression, with subsequent resistance to hormone therapy. ⋯ Regardless of our small sample size (n=44), the data obtained strongly suggest that MMP-2 in combination with already well-established markers could help to predict the emergence of metastases and death in patients with breast cancer.
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To describe the clinical features, imaging findings and pathological aspects of breast cancer diagnosed in women under the age of 40 years. ⋯ Most cases of breast cancer diagnosed in patients under the age of 40 years, in our population, had symptoms at diagnosis and tumor with more aggressive biological behavior. Despite the ultrasound has been the most widely used method, we found improved characterization of breast lesions when also used mammography and MRI.