Journal of thrombosis and haemostasis : JTH
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J. Thromb. Haemost. · Oct 2008
Multicenter StudyWarfarin for atrial fibrillation in community-based practise.
Previous studies of anticoagulation for atrial fibrillation (AF) have predominantly occurred in academic settings or randomized trials, limiting their generalizability. ⋯ Anticoagulation control varies widely among patients taking warfarin for AF. TTR is affected by new warfarin use, procedural interruptions, and INR target range. In this community-based cohort of predominantly prevalent warfarin users, rates of hemorrhage and stroke were low. The risk versus benefit of a lower INR target range to offset bleeding risk remains uncertain.