Chinese medical journal
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Chinese medical journal · Nov 2013
Meta AnalysisReplication of association study between type 2 diabetes mellitus and IGF2BP2 in Han Chinese population.
The association between IGF2BP2 and type 2 diabetes mellitus (T2DM) has been repeatedly confirmed among different ethnic populations. However, in several genome-wide association studies (GWAS) from the Chinese Han population, the gene IGF2BP2 has not been replicated. The results of relevant studies for the association between IGF2BP2 and T2DM showed controversy in Chinese Han population. It is necessary to systematically evaluate the contribution of common variants in IGF2BP2 to T2DM in Chinese Han population. ⋯ IGF2BP2 was strongly associated with the risk of T2DM in Chinese Han population.