Chinese medical journal
-
Chinese medical journal · Jun 2018
ReviewUrinary Extracellular Vesicle: A Potential Source of Early Diagnostic and Therapeutic Biomarker in Diabetic Kidney Disease.
Diabetic kidney disease (DKD) has become one of the major causes of end-stage renal disease. Urinary extracellular vesicles (uEVs) contain rich biological information which could be the ideal source for noninvasive biomarkers of DKD. This review discussed the potential early diagnostic and therapeutic values of proteins and microRNAs in uEVs in DKD. ⋯ Proteins and nucleic acids in uEVs represent promising biomarker for the diagnosis and treatment of DKD.