Chinese medical journal
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Chinese medical journal · Mar 2012
Meta AnalysisVitamin D receptor genetic polymorphisms and tuberculosis among Chinese Han ethnic group.
In epidemiological studies, tuberculosis (TB) appears intimately with vitamin D insufficiency whereas its relationship with vitamin D receptor (VDR) polymorphism caused by radical difference remains unspecified. This study aimed to investigate the relationship between vitamin D genetic polymorphism and tuberculosis in Han ethnic group. ⋯ The interaction between FoKI genotype polymorphism and TB observed demonstrates that vitamin D deficiency might exist as a risk factor during the development of TB in Han ethnic group and more evidences needed to validate the conclusion.
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Chinese medical journal · Jan 2012
Meta AnalysisEfficacy and safety of micafungin for invasive candida infections: a meta-analysis of randomized controlled trials.
Invasive fungal infections such as candidiasis and mold infections cause significant morbidity and mortality in seriously ill patients. Micafungin is an echinocandin antifungal agent with potent activity against most species of Candida and Aspergillus. We did this meta-analysis to clarify whether micafungin offers superior efficacy and safety compared with other antifungal agent for treating infections associated with invasive candidiasis. ⋯ Micafungin has a good safety and tolerability profile, with an efficacy at least comparable to the other antifungal agents. Micafungin offers advantages over other agents for antifungal prophylaxis. Micafungin offers an appropriate alternative for antifungal prophylaxis rather than the treatment of invasive candida infections.
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Chinese medical journal · Dec 2011
Meta AnalysisKnee function after anterior cruciate ligament reconstruction with patellar or hamstring tendon: a meta-analysis.
There is currently no consensus regarding the best graft type for anterior cruciate ligament reconstruction. Therefore, the aim of this study was to investigate the effects of patellar and hamstring tendon grafts on long-term knee function after anterior cruciate ligament reconstruction. ⋯ Anterior cruciate ligament reconstruction using patellar or hamstring tendon grafts results in similar long-term knee function.
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Chinese medical journal · Jul 2011
Meta AnalysisExcision repair cross complementation group 1 polymorphisms and lung cancer risk: a meta-analysis.
Several studies have evaluated the association between polymorphisms of encoding excision repair cross complementation group 1 (ERCC1) enzyme and lung cancer risk in diverse populations but with conflicting results. By pooling the relatively small samples in each study, it is possible to perform a meta-analysis of the evidence by rigorous methods. ⋯ We found little evidence of an association between the T1900C or C8092A polymorphisms of ERCC 1 and the risk of lung cancer in Caucasian or Han Chinese people.
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Chinese medical journal · Jun 2011
Review Meta AnalysisHeterosexual risk of HIV infection in China: systematic review and meta-analysis.
Heterosexual sex has become the dominant transmission route in China. Recently studies reported high heterogeneity in heterosexual transmission risk in resource-limited countries. The aim of this study was to summarize the risk of HIV transmission among Chinese serodiscordant couples. ⋯ Transmission estimates in China were lower than other developing countries, but higher than developed countries. Research that better defines HIV secondary transmission rates and the associated behavioral, treatment adherence, and health-related risk factors among heterosexual serodiscordant couples in China is needed.