Circulation
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Randomized Controlled Trial Multicenter Study
Effect of valsartan on systemic right ventricular function: a double-blind, randomized, placebo-controlled pilot trial.
The role of angiotensin II receptor blockers in patients with a systemic right ventricle has not been elucidated. ⋯ URL: http://www.controlled-trials.com. Unique identifier: ISRCTN52352170.
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Multicenter Study
Aortic root dilatation in adults with surgically repaired tetralogy of fallot: a multicenter cross-sectional study.
Although aortic root pathology has been described in patients with tetralogy of Fallot, the scope of the problem remains poorly defined. We sought to determine the prevalence and predictors of aortic root dilatation in adults with repaired tetralogy of Fallot. ⋯ Although nearly one third of adults with repaired tetralogy of Fallot have an aortic root diameter ≥40 mm, the prevalence of a dilated aortic root, when defined by an indexed ratio of observed-to-expected values, is low. Similarly, moderate or severe aortic regurgitation is uncommon.
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Randomized Controlled Trial Multicenter Study Comparative Study
Renal dysfunction as a predictor of stroke and systemic embolism in patients with nonvalvular atrial fibrillation: validation of the R(2)CHADS(2) index in the ROCKET AF (Rivaroxaban Once-daily, oral, direct factor Xa inhibition Compared with vitamin K antagonism for prevention of stroke and Embolism Trial in Atrial Fibrillation) and ATRIA (AnTicoagulation and Risk factors In Atrial fibrillation) study cohorts.
We sought to define the factors associated with the occurrence of stroke and systemic embolism in a large, international atrial fibrillation (AF) trial. ⋯ URL: http://www.ClinicalTrials.gov. Unique identifier: NCT00403767.