Circulation
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Randomized Controlled Trial Multicenter Study
What is the optimal chest compression depth during out-of-hospital cardiac arrest resuscitation of adult patients?
The 2010 American Heart Association guidelines suggested an increase in cardiopulmonary resuscitation compression depth with a target >50 mm and no upper limit. This target is based on limited evidence, and we sought to determine the optimal compression depth range. ⋯ http://www.clinicaltrials.gov. Unique identifier: NCT00394706.
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Growth differentiation factor 15 (GDF-15), high-sensitivity troponin, and N-terminal pro-brain natriuretic peptide levels are predictive of death and cardiovascular events in healthy elderly subjects, patients with acute coronary syndrome, and patients with heart failure. High-sensitivity troponin I and N-terminal pro-brain natriuretic peptide are also prognostic in patients with atrial fibrillation. We evaluated the prognostic value of GDF-15 alone and in addition to clinical characteristics and other biomarkers in patients with atrial fibrillation. ⋯ http://www.clinicaltrials.gov. Unique identifier: NCT00412984.