Circulation
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Randomized Controlled Trial Multicenter Study Comparative Study
Treatment of acute venous thromboembolism with dabigatran or warfarin and pooled analysis.
Dabigatran and warfarin have been compared for the treatment of acute venous thromboembolism (VTE) in a previous trial. We undertook this study to extend those findings. ⋯ www.clinicaltrials.gov. Unique identifiers: NCT00680186 and NCT00291330.
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Randomized Controlled Trial Comparative Study
High-sensitivity troponin I for risk assessment in patients with atrial fibrillation: insights from the Apixaban for Reduction in Stroke and other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial.
High-sensitivity troponin-I (hs-TnI) measurement improves risk assessment for cardiovascular events in many clinical settings, but the added value in atrial fibrillation patients has not been described. ⋯ http://www.clinicaltrials.gov. Unique identifier: NCT00412984.
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Randomized Controlled Trial Multicenter Study
Syncope in high-risk cardiomyopathy patients with implantable defibrillators: frequency, risk factors, mechanisms, and association with mortality: results from the multicenter automatic defibrillator implantation trial-reduce inappropriate therapy (MADIT-RIT) study.
There is a relative paucity of studies investigating the mechanisms of syncope among heart failure patients with implantable cardioverter-defibrillators, and it is controversial whether nonarrhythmogenic syncope is associated with increased mortality. ⋯ http://www.clinicaltrials.gov. Unique identifier: NCT00947310.